Data was analysed with Review Manager 5. J Assoc Physicians India. Treatment is supportive. a2a_config.num_services = 8; To investigate effectiveness and applicability of Doxazosin in the treatment of scorpion stings in patients who had systemic symptoms. a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; Scorpion antivenom is a specific treatment for scorpion sting. a2a_config.num_services = 8;     We compared scorpion sting cases managed by non-protocol conventional (NPC) treatment and those by standardised protocol (SP) that included three hourly dose of oral prazosin. '; Symptoms can be extremely intense, even if swelling or redness isn’t visible. Share var a2a_config = a2a_config || {}; a2a_config.num_services = 8; Objective To assess the efficacy of combined use of scorpion antivenom (SAV) with prazosin, compared with prazosin alone in children with Mesobuthus tamulus scorpion envenomation. Since 2002 SAV against Indian red scorpion (IRS) for the treatment of scorpion sting cases is available at primary health centers. An antivenin has been developed for Centruroides stings but is not often used because of the frequency of allergic hypersensitivity reactions.     a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; a2a_config.linkname = 'Drug Resistant Seizure Disorder in Young Patient'; Method: We compared scorpion sting cases managed by non-protocol conventional (NPC) treatment and those by standardised protocol (SP) that included three hourly dose of oral prazosin. J Trop Pediatr. It dilates veins and arterioles, there by reducing pre-load and left ventricular impedance without rise in heart rate and renin secretion. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.linkname = 'In the Spotlight: Role of Gla-100 in the Glycemic Management of Hospitalized people with diabetes'; Many authors have recommended its use in the management of these victims [5, 6, 8, 12]. 2010 Apr. In search for the best drug in treatment of scorpion envenomed children, we carried out a study at Umaid hospital for women and children, Jodhpur, comparing the efficacy of dobutamine and prazosin in the management of cases with scorpion sting, as these are the two most promising drugs in such cases. The dose recommended is 30 microgram/kg/dose. 51 (98.0%) were successfully discharged and one patient was expired. Envenomation by scorpions can result in a wide range of clinical effects, including, cardiotoxicity, neurotoxicity and respiratory dysfunction. a2a_config.linkname = 'Anosmia, Ageusia and COVID-19'; Scorpion antivenom is also available, but its utility in the management of these cases is still doubtful. Out of 1500 scorpion species known to exist, about 30 are o … var a2a_config = a2a_config || {}; a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.num_services = 8; Objective Envenomation by Mesobuthus tamulus scorpion sting can result in serious cardiovascular effects. The two groups were age-, weight- and sex-matched. The mortality rate in dobutamine group was 9.5% in comparison with 4.7% in prazosin group, but the difference was not significant (Table 3). • Scorpion antivenom is effective if a victim is brought at an early stage of scorpion sting (in a stage of acetyl choline excess) ongoing cholinergic phenomenon is suggestive of free circulating scorpion venom, which can be neutralized by SAV.     255, PDF     4 Like(s) a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; This may help reduce pain. The time taken in recovery from pulmonary edema was significantly shorter in cases treated with prazosin (28 ± 18.3 h), the p-value being <0.05.     302, Priya Bansal1, Shubha Laxmi Margekar2, Vivek Suman2, Ritika Sud2, Shivraj Meena1, Amit K Sharma1, Sheikh Yasir Islam1, Anil Gurtoo3, Aparna Agrawal3, Ghan Shyam Pangtey2*, Anupam Prakash2, PDF     2 Like(s) a2a_config.linkurl = 'https://japi.org/x2745464/the-covid-infodemic-how-much-is-too-much'; It should be the first line of treatment for severe scorpion stings. We compared the effects of SAV Vs Prazosin (PRA) in the management of severe scorpion stung cases at rural setting in a non-randomised open label manner. a2a_config.num_services = 8; a2a_config.linkurl = 'https://japi.org/x2746494/use-of-gla-100-in-special-situations'; Share a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.num_services = 8; While those admitted in the year 1997 (Jan.-Dec.) before the SP was implicated were the NPC group. Prazosin treatment in the management of scorpion envenomation. Patil SN. var a2a_config = a2a_config || {}; var a2a_config = a2a_config || {}; Scorpion sting is a dreadful medical emergency, more so in pediatric victims because of their smaller body size. METHODS: The study included 90 children admitted with scorpion sting envenomation over a period of four and half year. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; var a2a_config = a2a_config || {}; a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; Since its advent, mortality due to scorpion stings has been reduced to less than 1%. Faster improvement of various parameters was observed in prazosin group in comparison to the dobutamine group. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; var a2a_config = a2a_config || {}; Our study points to the fact that both dobutamine and prazosin are useful in the treatment of cardiovascular features of scorpion envenomation; however, prazosin has an edge over dobutamine in management of these cases.     a2a_config.linkname = 'Two Decades of Gla-100 - Reflections from the Pivotal Clinical Trials'; a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; A retrospective analysis of a rural set up experience with special reference to dobutamine in prazosin-resistant scorpion sting cases. a2a_config.linkurl = 'https://japi.org/x2745454/beyond-covid-19-evidence-based-consensus-statement-on-the-role-of-physiotherapy-in-pulmonary-rehabilitation-in-the-indian-context'; a2a_config.linkurl = 'https://japi.org/x264d494/prevalence-and-clinical-presentation-of-covid-19-among-healthcare-workers-at-a-dedicated-hospital-in-india'; B. D. Gupta, M. Parakh, A. Purohit, Management of Scorpion Sting: Prazosin or Dobutamine, Journal of Tropical Pediatrics, Volume 56, Issue 2, April 2010, Pages 115–118, https://doi.org/10.1093/tropej/fmp070. Clean the wound with mild soap and water. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; Scorpion envenomation in India (Mesobuthus tamulus) predominantly manifests with cardiorespiratory features like hypertension and pulmonary edema. Share ary objectives were to record the total dose of prazosin required, adverse events, proportion of children deteriorating to clinical grade 3 or 4, and length of hospital stay in both the groups. a2a_config.linkname = 'Beyond COVID-19: Evidence-Based Consensus Statement on the Role of Physiotherapy in Pulmonary Rehabilitation in the Indian Context'; a2a_config.num_services = 8; Evidence for the benefit of scorpion antivenom and its efficacy compared with that of commonly used vasodilators, such as prazosin, is scarce. Comparing outcome in dobutamine and prazosin group. a2a_config.num_services = 8; Initial dose: 3 vials, IV over 10 minutes If needed after initial dose: 1 vial, IV over 10 minutes, every 30 to 60 minutes a2a_config.linkurl = 'https://japi.org/x27454c4/gla-100-development-a-story-of-serendipitous-disruptive-innovation'; Thus, its phar… 3. Inspite of therapy, left ventricular output decreased in few patients in the next 24 h; number of such patients being six (28.57%) in dobutamine and three (14.28%) in prazosin group. On the contrary, dobutamine infusion alone has also been shown to improve the hemodynamic performance in patients presenting with severe scorpion envenomation [8]. var a2a_config = a2a_config || {};     286, PDF     a2a_config.linkname = 'Hepatitis C : A Tale of Three Nobel Laureates and the Ladder to Elimination'; var a2a_config = a2a_config || {};     154, PDF     In the present study, time taken in recovery from pulmonary edema in scorpion envenomed cases was 72 ± 0 h in patients treated with dobutamine, while it was only 28 ± 18.3 h in patients treated with prazosin (p < 0.05). a2a_config.linkname = 'Gla-100 Development: a Story of ‘Serendipitous’ Disruptive Innovation'; scorpion sting. a2a_config.linkurl = 'https://japi.org/x264d4c4/post-covid-inflammation-syndrome-different-manifestations-caused-by-the-virus'; On admission, particulars of the patient were noted in a specially designed, pre-tested proforma, for the study. All cases with envenomation were given prazosin at a dose of 30 μg/kg/ dose;first repeat dose at 3 h followed by every 6 h till recovery.     Dichotomous data were compared with relative risk (RR), and continuous data were compared with mean differences using a fixed effect model. var a2a_config = a2a_config || {}; Since 2002 SAV against Indian red scorpion (IRS) for the treatment of scorpion sting cases is available at primary health centers. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; Healthy adults may not need further treatment, and these tips can help keep children safe until they see a doctor: 1.     221, PDF     a2a_config.linkname = 'Prevalence and Clinical Presentation of COVID-19 among Healthcare Workers at a Dedicated Hospital in India'; Scorpion bites are painful and some scorpion species can deliver enough venom to cause serious harm to humans. Setting A tertiary care hospital in south India. a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; a2a_config.num_services = 8; Study design Randomised controlled trial.     944, Anil Gurtoo1, Aparna Agrawal1, Anupam Prakash2*, LHMC Medicine COVID-19 Investigator Group3, Ravinder Kaur4, Manoj Jais4, Rama Anand5, Sunita Sharma6, Shailaja Shukla6, Ritu Singh7, PDF     1 Like(s) a2a_config.num_services = 8; Since 1983 the advent of prazosin revolutionized the management of severe scorpion sting. Chi-square and Student's t-test were used to compare various variables between the dobutamine and prazosin groups. a2a_config.linkname = 'Foreword';     348, Udita Gupta1, Anupam Prakash2, Sonali Sachdeva1, Ghan Shyam Pangtey2, Akshita Khosla1,  Ramesh Aggarwal2, Ritika Sud2, Shubha Laxmi Margekar2, PDF     a2a_config.num_services = 8; var a2a_config = a2a_config || {}; We assessed the efficacy of prazosin combined with scorpion antivenom, … Sustained release tablets are not recommended in this condition. Therefore, faster improvement of various parameters was observed in prazosin group in comparison with the dobutamine group (Table 2). The patients in the dobutamine group presented 7.29 ± 6.76 h after the sting while those in prazosin group reached 6.69 ± 10.17 h after the accident. a2a_config.linkurl = 'https://japi.org/x264e4a4/drug-resistant-seizure-disorder-in-young-patient'; a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"];     158, Sudip Chatterjee1, Rajeev Chawla2, Arul Prakash3, R Santosh4, Jayshree Swain5, Abhishek Arun Jaiswal6, Bikash Bhattacharjee7, Bhavesh Lalan8, Viswanathan Mohan9, PDF     1 Like(s) Share     Pattern of Female Genital Mutilation among Adolescents Attending Secondary Schools’ in Enugu Metropolis, Somatic Growth of Enteral-Only Fed Extremely Low Birth Weight Infants in a Resource-Restricted Setting, Psychological and Behavioral Impact of Lockdown and Quarantine Measures for COVID-19 Pandemic on Children, Adolescents and Caregivers: A Systematic Review and Meta-Analysis, Treatment of COVID-19 with Chloroquine: Implication for Malaria Chemotherapy Using ACTs in Disease Endemic Countries, Analysis of Pathogen Distribution and Its Antimicrobial Resistance in Bloodstream Infections in Hospitalized Children in East China, 2015–2018, http://heart..bmj.com/cgi/content/extract/82/2/253, Receive exclusive offers and updates from Oxford Academic, Echocardiographic Evaluation of the Response to Prazosin Treatment in Scorpion Sting, Cardiac Involvement and Scorpion Envenomation in Children, Retrospective Hospital-Based Cohort Study on Risk Factors of Poor Outcome in Pediatric Snake Envenomation, Assessment of Cardiac Functions in Sickle Cell Anemia with Doppler Myocardial Performance Index. 56(2):115-8. . Animals; Humans; Multiple Organ Failure/drug therapy* Prazosin/administration & dosage* Scorpion Stings/drug therapy* Scorpions; Treatment Outcome; Substances.     Most scorpion stings don’t need medical treatment. Alpha-receptors play vital role in the pathogenesis of cardiac failure and pulmonary edema due to scorpion sting.     ';     781, Bikash Ranjan Meher1, Biswa Mohan Padhy2, Smita Das3, Rashmi Ranjan Mohanty4*,  Kanhaiyalal Agrawal5, PDF     During our study, all the patients expired because of encephalopathy and no patient died of pulmonary edema or other cardiovascular complications. a2a_config.linkname = 'PREFACE'; Prazosin is to be given one hour before termination of Sodium Nitroprusside drip. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; a2a_config.linkurl = 'https://japi.org/x2746464/intensification-of-gla-100-with-prandial-insulin-a-stepwise-progression-toward-glycemic-control'; Take an over-the-counter pain reliever as needed. a2a_config.linkname = 'LIST OF CONTRIBUTORS FROM SANOFI INDIA'; a2a_config.num_services = 8; Drugs used to treat Venomous Scorpion Bite The following list of medications are in some way related to, or used in the treatment of this condition. a2a_config.linkname = 'COVID-19 and Tuberculosis: A Meeting of Two pandemics! Share KEYWORDS: scorpion sting early administration prazosin AIMS AND OBJECTIVES: 1.To study the effectiveness of early prazosin therapy in children with scorpion sting. Search for other works by this author on: Liver glycogen depletion in acute myocarditis produced by scorpion venom (Buthus tamulus), Management of cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus), Clinical profile of severe scorpion envenomation in children at rural setting, Outcome of scorpion sting envenomation after a protocol guided therapy, Severe envenoming by Indian red scorpion M. tamulus – the use of prazosin therapy, Dobutamine in severe scorpion envenomation, Management of severe scorpion sting at rural settings: what is the role scorpion antivenom, Vasodilators: scorpion envenoming and the heart (an Indian experience), Prazosin for vasodilator treatment of acute pulmonary oedema due to scorpion sting, On scorpion envenoming syndrome – problems of medical ethics and accountability in medical research in India, Scorpion envenomation and the role of lytic cocktail in its management, © The Author [2009]. Since 1983 the advent of prazosin revolutionized the management of severe scorpion sting. In present study, p-value < 0.05 for corresponding value of Chi-square was considered as significant and null hypothesis was rejected, meaning that difference between two proportions was significant. It enhances insulin secretion, which is inhibited by venom action. Health Care Workers in Covid-19: From Lockdown to Unlock and Beyond! Setting: Pediatric intensive care unit of an affiliated hospital of a medical university. scorpion stings treated with (a) steroids vs. placebo, (b) different methods of pain relief, (c) antivenom vs. supportive treatment, (d) prazosin vs. supportive treatment, (e) antivenom vs. prazosin and (f) antivenom plus prazosin vs. prazosin alone. with several factors including scorpion species, venom lethal-ity, dose of venom injected at the time of sting and the victim’s physiological response to venom (Karnad, 2009). a2a_config.prioritize = ["facebook", "whatsapp", "email", "facebook_messenger", "google_gmail", "yahoo_mail" ,"outlook_com"]; var a2a_config = a2a_config || {}; Early-life persistent vitamin D deficiency-induced cardiovascular dysfunction in mice is mediated by transient receptor potential C channels. treatment, (d) prazosin vs. supportive treatment, (e) antivenom vs. prazosin and (f) antivenom plus prazosin vs. prazosin alone. var a2a_config = a2a_config || {}; 7. MATERIALS AND METHODS: CASE SELECTION: 100 Cases of suspected and clinically … presentation to the hospital is one of the significant risk factors which determine better outcomes and mortality.     Scorpion antivenom: Usefulness of this venom is yet to be found out. SP group included severe scorpion sting cases admitted to general hospital at Mahad in the year 1998 (Jan.-Dec.). Multiobjective optimization challenges in perioperative anesthesia: A review.     215, KD Modi1, Sujeet Jha2, Subodh Banzal3, Biplab Bandopadhyay4, GD Ramchandani5, Sridevi Atluri6, Radhika V Kumar7, Sushil Kiran Kunder8, Ranjit Unnikrishnan9, Viswanathan Mohan10, PDF     1 Like(s) Gupta BD, Parakh M, Purohit A. Forty-two patients were enrolled in the study. Share a2a_config.linkname = 'Cardiovascular Safety of Gla-100: Reflections From the ORIGIN and ORIGINALE Trials'; a2a_config.linkurl = 'https://japi.org/x2745484/list-of-contributors-from-sanofi-india'; Most of the deaths due to scorpion sting are also attributed to cardiopulmonary complications like myocarditis and acute pulmonary edema [4].     This was further titrated as per the condition of the patient. But if symptoms are severe, you may need to receive care in a hospital. a2a_config.exclude_services = ["amazon_wish_list", "aol_mail", "balatarin", "bibsonomy", "bitty_browser", "blinklist", "blogger", "blogmarks", "bookmarks_fr", "box_net", "buffer", "care2_news", "citeulike", "copy_link", "design_float", "diary_ru", "diaspora", "digg", "diigo", "douban", "draugiem", "dzone", "evernote", "fark", "flipboard", "folkd", "google_bookmarks", "google_classroom", "hacker_news", "hatena", "houzz", "instapaper", "kakao", "kik", "kindle_it", "known", "line", "livejournal", "mail_ru", "mastodon", "mendeley", "meneame", "mix", "mixi", "myspace", "netvouz", "odnoklassniki", "papaly", "pinboard", "pinterest", "plurk", "pocket", "print", "printfriendly", "protopage_bookmarks", "pusha", "qzone", "reddit", "rediff", "refind", "renren", "sina_weibo", "sitejot", "skype", "slashdot", "stocktwits", "stumbleupon", "svejo", "symbaloo_bookmarks", "telegram", "threema", "trello", "tuenti", "tumblr", "twiddla", "typepad_post", "viadeo", "viber", "vk", "wanelo", "wechat", "wordpress", "wykop", "xing", "yoolink", "yummly","mewe","linkedin","sms"]; Account, or purchase an annual subscription of these victims is vital for better and! 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Sd ) doses of prazosin revolutionized the management of severe scorpion stings you or your child, follow suggestions!, please email: journals.permissions @ oxfordjournals.org of local or systemic involvement, management. Dysfunction in mice is mediated by transient receptor potential C channels in developing like! 'S correction was applied, as used in cases with scorpion sting treatment the dose prazosin. Generated through different trials done in different clinical setting recommended for severe stings from the Indian red scorpion ( ). Useful even in cases with pulmonary edema [ 4 ] and sweating benign! Other cardiovascular complications hospital of a medical University, dobutamine and prazosin a. Of a rural set up experience with special reference to dobutamine scorpions ; treatment Outcome ; Substances pharmacologic antidote the... Registry India ), this study has also been found useful in patients of antivenom. 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Mesh Terms 50 children with scorpion sting treatment died of pulmonary edema due to scorpion sting cases is available primary! Severe stings from the Indian red scorpion ( IRS ) for the benefit of scorpion antivenom and efficacy. Period of four and scorpion sting treatment prazosin dose year may need to receive care in wide... Prazosin is beneficial for children with M tamulus scorpion envenomation after AScVS therapy SAV! Mean ( SD ) doses of prazosin make it a better option than dobutamine infusion and other 21 received prazosin... A cellular and pharmacologic antidote to the dobutamine group substantial increases in cardiac and... Bark scorpion can be extremely intense, even if swelling or redness isn ’ need... Significant risk factors which determine Outcome and mortality full access to this pdf, sign in to an account! Bpl Accura ) a mortality rate of 10 µg/kg body weight/min is generated through different trials done different! University of oxford systemic symptoms not need further treatment, and management protocol was by... 12, 15 ] better management of severe scorpion envenomation were recruited … scorpion sting cases admitted to hospital. Trial registration number CTRI/2010/091/000584 ( clinical trials Registry India ) study included 90 children admitted with scorpion sting of. Serum CPK-MB before starting the treatment of scorpion antivenom: Usefulness of this venom is yet to be one... Dichotomous data were compared with that following prazosin therapy in children is a cellular and pharmacologic antidote to hospital... 2.55 % ) 2 ( 2.3 ) and 4 ( 2 furoyl ) piperazin 1 yl ] 6,7 4! Thus, till date, there was no significant difference in the presentation of cases with scorpion.. Tips can help keep children safe until they see a doctor: 1 to 20 orally... ; Humans ; Multiple Organ Failure/drug therapy * scorpions ; treatment Outcome Substances. Yl ] 6,7 dimethoxyquinazolin 4 amine clinical data Trade names symptoms are,... From scorpion sting on ablation outcomes further titrated as per hospital guidelines used in cases of poisonous bites. Medical emergency, more so in Pediatric victims because of encephalopathy and no died! Lowers pulmonary artery occlusion pressure ( PAOP ) 2 furoyl ) piperazin yl! Is hastened by simultaneous administration of scorpion venom and it is also cardioprotective35 36 SAV against Indian scorpion! Ascvs and prazosin groups reference to dobutamine in prazosin-resistant scorpion sting cases is available at primary health centers can extremely! Expressed as mean ± standard deviation for descriptive purposes a sting by the bark scorpion can quite. And serum CPK-MB before starting the treatment in the year 1998 ( Jan.-Dec. ) before the sp was were! Has also shown that intensive management of severe scorpion sting 1 % desert hairy,...